Figure 4
![Figure 4. Inhibitory effect of RAP on the interaction of the (β15-66)2 fragment with the VLDLR detected by SPR. (A) RAP (50nM; solid line), 500nM (β15-66)2 (dotted line), or their mixture [50nM RAP + 500nM (β15-66)2] (broken line), were added to immobilized VLDLR and their association/dissociation was monitored in real time. (B) The same mixture of RAP and (β15-66)2 was added after the addition of 50nM RAP (solid line) or 500nM (β15-66)2, (broken line); arrows indicate injection of the mixture. The curves are representative of 2 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/119/2/10.1182_blood-2011-09-382580/5/zh89991184400004.jpeg?Expires=1735564794&Signature=WFHAZ9r1pOIeToCzuj7sb~qf3gCP8rV7ncWRhX9VcUt0DEgejhT685zyOwbvAAxHKiqwye~pFCdk9k84IM5TK2WHWrswEQh431ilqzJ9NapJNiJWwKAXF788fRQYJTtmK-pOBbkPiVlejswMrxQCeYkapzhlpdol0URMkWdF-LvldLpe4APb0-ZzIZfW2O5biP~PLdr28dnbisfpJttLPD9Gop4DVTC2Wdik4wIPiNAis0ueeC6cZP4TG7dN-JhtWDq6wpwvlUoVnEAianVnRPvPx~Wqw3A-aIM-CtpL4xA3U0gz~bHhya-wGURjllx~Tjf2dx9yHz0E2gwCEvT-KA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Inhibitory effect of RAP on the interaction of the (β15-66)2 fragment with the VLDLR detected by SPR. (A) RAP (50nM; solid line), 500nM (β15-66)2 (dotted line), or their mixture [50nM RAP + 500nM (β15-66)2] (broken line), were added to immobilized VLDLR and their association/dissociation was monitored in real time. (B) The same mixture of RAP and (β15-66)2 was added after the addition of 50nM RAP (solid line) or 500nM (β15-66)2, (broken line); arrows indicate injection of the mixture. The curves are representative of 2 independent experiments.
