Mapping of 168 TP53 mutations in 141 CK-AMLs. Hemizygous mutations are indicated in the bottom panel, heterozygous, and/or homozygous mutations are marked in the top panel. Exons 4 to 10 are drawn to relative scale; missense mutations (green), nonsense mutations (red), and insertion/deletion mutations (blue) are shown at their approximate location along the exons. Bold represents homozygous mutations, and blue italics, frameshift mutations leading to a premature stop codon.