Baseline levels of total Vγ9Vδ2 T cells and EM + TEMRA subsets affect TTFT. Patients were allocated to Vγ9Vδ2_low/Vγ9Vδ2_high and EM + TEMRA_low/EM + TEMRA_high categories on the basis of their baseline count of total Vγ9Vδ2 T cells and EM + TEMRA subpopulations. Median values of baseline count of total Vγ9Vδ2 T cells and EM + TEMRA subsets calculated for the entire group of patients were used as cut-off level. (A) TTFT was significantly longer in Vγ9Vδ2_low compared with Vγ9Vδ2_high patients (median TTFT not reached and 42 months, respectively, P = .014). (B) TTFT was significantly longer in EM + TEMRA_low, compared with EM + TEMRA_high patients (median TTFT not reached and 42 months, respectively, P = .02).