NSC697923 inhibits the proliferation and survival of GCB-DLBCL cells. (A) GCB-DLBCL cells were plated at the indicated cell concentrations and treated with various concentrations of NSC697923 for 24 hours. The effects of NSC697923 on the growth of these cells were analyzed as described in Figure 5C. (B) The cells were plated at a concentration of 4 × 105 cells/mL and treated with NSC697923 as in panel A and the apoptotic cells were analyzed as described in Figure 5E. (C) Cell-cycle distribution of OCI-Ly7 cells treated with the indicated concentrations of NSC697923 for 24 hours. Shown are the average results from 2 independent experiments.