Table 1.
The genetics of aHUS: comparison of European and US aHUS cohorts
For comparison purposes, data were derived from the largest European Cohort (N = 273)4 and the single US cohort (N = 144).7 CFH fusion proteins were not reported in either cohort. The term “unknown” is used to designate patients with the absence of mutations after genetic screening for known aHUS genes. Bold type indicates those proteins that are produced by the liver and therefore are theoretically amenable to liver transplantation. Reported reasons for transplantation loss at 1 y were aHUS recurrence, acute rejection, or thrombosis.
