OS and PFS according to the treatment and GC/ABC classified by the gene predictor based on gene signatures.³⁴  Gray lines indicate patients with a GCB profile (n = 19, 51%). Red lines indicate patients with an ABC profile (n = 18, 49%). Patients with GCB-like DLBCL treated with R-DHAP had a significantly better PFS and OS than patients with ABC-like DLBCL treated with R-DHAP. Patients treated with R-ICE had poor survival regardless of the molecular subtype. Adapted by Catherine Thieblemont from Thieblemont et al.¹⁵