Proposed risk stratification strategy for perioperative thromboembolism (adapted from Douketis et al1,12 )
CHF indicates congestive heart failure; TIA, transient ischemic attack and VTE, venous thromboembolism.
*The CHADS2 score is calculated by the cumulative score for congestive heart failure (1 point), hypertension (1 point), age > 75 y (1 point), diabetes mellitus (1 point), and previous stroke or TIA (2 points).13
†“Severe” thrombophilias include deficiency of protein C, protein S, or antithrombin, antiphospholipid antibodies, or multiple abnormalities (eg, compound heterozygosity for factor V Leiden and prothrombin G20210A). “Nonsevere” thrombophilias include heterozygosity for factor V Leiden or prothrombin G20210A. The clinical relevance for these inherited risk factors in predicting risk of recurrent VTE, however, is unclear.14
