RvD4 treatment enhances thrombus resolution in mice. (A) Representative Doppler ultrasonography images of IVC thrombi obtained from the same mouse at the indicated time points after IVC stenosis induction. The red represents arterial flow, the blue is venous flow, and the thrombus is outlined in cyan. Scale bars, 2.5 mm. (B) Thrombus size was monitored by ultrasonography on day 1, day 4, and day 8 postsurgery. n = 5 mice in the vehicle-treated group (●), and n = 8 in the RvD4-treated group (▪). *P < .05, with 2-tailed unpaired t test for vehicle vs RvD4. (C) Network pathway visualization of the LMs in the thrombus after RvD4 treatment. Node size represents the amount of LMs (pg/10 mg of thrombus) in the thrombus after RvD4 treatment. Node color represents the fold change (compared with vehicle treatment).