Recovery of T cells with regulatory and recent thymic emigrant phenotypes. Numbers (A) and percentages (B) of CD4 T cells with a regulatory phenotype. Short horizontal lines indicate the median values at each time. Horizontal dotted lines enclosing gray boxes represent the median and interquartile range of 11 adult healthy volunteers. Comparisons between patients at each time and healthy volunteers were performed using a 2-tailed Mann-Whitney U test. (C) Numbers of naive CD4 T cells expressing CD31, which indicates recent thymic emigrants (RTEs). Patients older than 50 years are indicated by filled circles and those younger than 50 years are indicated by white triangles. Horizontal dotted lines enclosing gray boxes represent the median and interquartile range of 11 adult healthy volunteers. Significant differences are indicated with ***P < .0005; **P < .005.