Lower cell death after stimulation of apoptosis by FAS-L/TRAIL and reduction of CASP8 and PARP cleavage due to reduced activity of CASP10 protein in our patient (pt) compared to the control. (A) Apoptosis proteins cleavage and cell death induced by FAS-L (10 ng/mL); values given as percentage. (B) Apoptosis proteins cleavage and cell death stimulated by TRAIL (100 mM); values given as percentage. cl, cleaved; wt, wild type.