Predicted EFS and CIR in patients with MRD post-HCT according to their pre-HCT MRD level. (A-C) Model-based EFS. (D-F) A model-based CIR. The model is presented in Figure 1B. The lines represented the predicted outcome for reference children with MRD assessed on day +30 after HCT. The red solid lines represent the outcome for reference children whose MRD was negative. The dashed light green lines show the predicted outcome for reference children whose MRD was low. Analogously, the blue solid lines illustrate the reference children whose MRD measurements were high, and the dashed purple lines represent the predicted outcome for reference children with MRD very high. In addition, panels A and D are the prediction considering MRD before HCT = low, panels B and E are the prediction considering MRD before HCT = high, and panels C and F are the prediction considering MRD before HCT = very high.