Demethylating agent DAC upregulates TAZ and represses MYC transcriptional program. KMM1 (A), KMS11 (B), JJN3 (C), and U266 (D) were treated with increasing concentrations of DAC and evaluated for TAZ and MYC expression at the mRNA and/or protein levels. KMM1 (E) or JJN3 (F) cells were treated with increasing concentrations of DAC and evaluated for deregulation of MYC targets at the mRNA level. Data are mean ± SD of triplicate samples.