Best percent change from baseline in disease burden. The best percent change in tumor size for 68 patients eligible for efficacy analysis was determined by the principal investigators. One patient was not evaluable for change in tumor size due to lack of a post-baseline scan. Each bar represents an individual patient. Patients are grouped according to histology. MCL, mantle cell lymphoma; RT, Richter’s transformation. *Post-baseline scan was not available for 1 patient with MCL.