Figure 2.
Kinetics of expansion of JAK2-mutated cells in PF4iCre;mT/mG;JAK2V617F/WTmice. Frequencies of GFP-expressing cells were assessed in the different cell populations in the blood (panel A, n = 4-12 JAK2WT; n = 5-14 JAK2V617F), in the bone marrow precursors (panel B, n = 5-9 JAK2WT; n = 4-5 JAK2V617F), and progenitors (panel C, n = 3-7 JAK2WT; n = 3-7 JAK2V617F). Data are presented as mean ± standard error of the mean. Statistical significance determined by unpaired t test. *P < .05, **P < .01, ***P < .001.

Kinetics of expansion of JAK2-mutated cells in PF4iCre;mT/mG;JAK2V617F/WTmice. Frequencies of GFP-expressing cells were assessed in the different cell populations in the blood (panel A, n = 4-12 JAK2WT; n = 5-14 JAK2V617F), in the bone marrow precursors (panel B, n = 5-9 JAK2WT; n = 4-5 JAK2V617F), and progenitors (panel C, n = 3-7 JAK2WT; n = 3-7 JAK2V617F). Data are presented as mean ± standard error of the mean. Statistical significance determined by unpaired t test. *P < .05, **P < .01, ***P < .001.

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