American Society of Hematology

Figure 5.

Logistic regression of antioxidogram RQ values to define the AO-Score. AO-Score was calculated as follows: AO-Score = ∑i=1nC(i)∗RQ(i)+intercept, C(i) and RQ(i) being weighted coefficients and relative quantification of gene i, respectively, and n the number of genes in the model. (A) Weighted coefficients of 7 transcripts allowed the discrimination between patients with MDS with <5% BM blasts or MDS with 5% to 19% BM blasts plotted in a vertical axis. (Right) Calculated weighted values (AO-Score) plot. (B) Weighted coefficients of 4 transcripts allowed the discrimination between MDS with 5% to 19% BM blasts and sAML patients. Significant difference (AO-Score values), P < .05.

Logistic regression of antioxidogram RQ values to define the AO-Score. AO-Score was calculated as follows: AO-Score = $\sum_{i = 1}^{n} C (i) * R Q (i) + i n t e r c e p t$ ⁠, C(i) and RQ(i) being weighted coefficients and relative quantification of gene i, respectively, and n the number of genes in the model. (A) Weighted coefficients of 7 transcripts allowed the discrimination between patients with MDS with <5% BM blasts or MDS with 5% to 19% BM blasts plotted in a vertical axis. (Right) Calculated weighted values (AO-Score) plot. (B) Weighted coefficients of 4 transcripts allowed the discrimination between MDS with 5% to 19% BM blasts and sAML patients. Significant difference (AO-Score values), P < .05.

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