Figure 4.
Pattern of possible epitope spreading observed in patients with increasing numbers of glycoprotein-specific autoantibodies on interval testing. Median durations between assays given. White text delineates new autoantibodies present in subsequent assay not present in previous assay. Platelet count at the time of testing was similar at first test compared with repeat test (88 × 109/L at first test and 71 × 109/L at repeat test, P = .17 by paired Student t test).