Alterations in the peripheral T cell compartment in CD11c^ΔMHCIImice. WT and CD11c^ΔMHCII mice were assessed by flow cytometry for the T cell compartment at 12 weeks (n = 11, 13), 20 weeks (n = 22, 16), 30 weeks (n = 18, 11), and 1 year (n = 22, 25) of age. (A) Percentages of T cell subsets in the thymus at 30 weeks (n = 6, 7). (B) Percentages of total CD4⁺ T cells among total splenocytes. (C) Percentages of naive CD4⁺ T cells (CD4⁺CD62L⁺CD44⁻) among CD4⁺ T splenocytes. (D) Percentages of Treg cells (CD4⁺Foxp3⁺) gated on splenic CD4⁺ T cells. (E) Percentages of CD8⁺ T cells among total splenocytes. (F) Percentages of effector CD8⁺ T cells (CD8⁺CD62L⁻CD44⁺) gated on splenic CD8⁺ T cells. Median and individual data points are shown.