This figure demonstrates evidence of significant fractional shortening in all mice receiving Cfz without much variability. In protocol 2, the Cfz dose was equivalent to a human dose of 14.85 mg/m² and was given for 2 days. In protocol 3, the Cfz dose was equivalent to a human dose of 29.65 mg/m² given every other day for 4 doses. ***P = .001, ****P < .001. The figure was adapted from Figure 1E-F in the article by Efentakis et al that begins on page 710.