Evolution of molecular analysis techniques in myeloma. Images from left to right show G-band karyotyping, FISH, GEP data, SNP array data, and NGS data. Karyotype images were reprinted from Panagopoulos et al.⁸⁸  FISH images were reprinted from Fernando et al.⁸⁹  GEP images were reprinted from André et al.⁹⁰  SNP array and NGS images were reprinted from Bolli et al.⁹¹