PP2A as a main mediator of Cfz-induced cardiotoxicity. (A) Graph of PP2A activity (pmol/min per milligram protein/mL) is expressed as fold change in comparison with controls. Representative western blot and relative densitometric analysis of PP2A in (B) protocol 2, (C) protocol 3, (D) protocol 5A, (E) protocol 6A, and (F) protocol 6B. *P < .05, **P < .01, ***P < .001 n = 4-6 per group. Western blots show 3 representative animals from each experimental group, 1 in each lane.