Figure 3.
Effect of factors associated with better EFS in multivariable model. (A-B) Log relative hazard effect relationship with the prelymphodepletion serum LDH concentration and platelet count, demonstrating increasing relative hazard with higher LDH or lower platelet count, respectively. The standard error is shown in pink; dashed line indicates the upper limit of normal of LDH concentration and lower limit of normal of platelet count. (C-D) Kaplan-Meier analyses demonstrate better EFS and OS in patients with low-risk characteristics (receiving fludarabine-containing lymphodepletion with a prelymphodepletion LDH concentration in the normal range, and platelet count >100 000/μL) identified by stepwise multivariable modeling (blue line) compared with those with high-risk characteristics (red line).