Cumulative frequency of BCR-ABL1 testing over the course of the first 12 months following TKI cessation using the various testing algorithms demonstrated in Figure 1. (A) Theoretical cohort of 100 patients. (B) Real cohort. One hundred seven real patients who underwent a TFR attempt and were monitored at our institution. (C) Predicted effect of detection delays based upon algorithms B-D for the 107 real patients.