Antibody-mediated TRALI is associated with increased pulmonary PMN accumulation in WT mice. Lung W/D weight ratios (A) and percentage of pulmonary PMNs (B) in C57BL/6 WT mice primed with LPS, depleted of CD4⁺ T cells, and injected (or not) with anti-MHC class I antibodies (clones 34-1-2s and AF6-88.5.5.3). Statistical analysis was performed with a 1-tailed unpaired Student t test. Each dot represents 1 mouse and error bars represent SD. ****P < .0001.