GSK3 is essential for lymphoma cell proliferation and survival. Unstimulated peripheral blood B and T lymphocytes isolated from a healthy donor were used as normal control. Proapoptotic effect of the GSK3 inhibitor 9-ING-41 in various MCL and TCL lines (A) and in DLBCL lines (B). (C) Cell-proliferation profile of various lymphoma cell lines upon treatment with 9-ING-41. All results are from 3 independent experiments.