Depletion of primitive macrophages has little effect on definitive hematopoiesis. (A-B) WISH of hbae1 shows erythropoiesis is not affected in cebpa^rj31 mutant compared with control sibling. (A′-B′) Magnified images of corresponding boxed regions from panels A and B. (C-D) WISH of rag1 shows lymphopoiesis is relatively normal in cebpa^rj31 mutant compared with control sibling. dpf, days postfertilization.