Figure 4.
Figure 4. PAMPs induce overlapping procoagulant and proinflammatory responses in human monocytes. PBMCs were stimulated for 6 hours with PGN (10 µg/mL), heat-killed (hk) B anthracis (107 CFU/mL), LPS (1 µg/mL), or Pam3CSK4 (1 µg/mL) in the presence of BFA before intracellular quantification of TF and TNF-α by flow cytometry. (A) Representative distribution of procoagulant (TF+) and proinflammatory (TNF-α+) responses in PAMP-stimulated monocytes. (B) Average distribution of procoagulant and proinflammatory responses in PAMP-stimulated monocytes in the cohort studied (n = 11). Column segments represent mean and standard deviation for each population depicted in the legend. FITC, fluorescein isothiocyanate.

PAMPs induce overlapping procoagulant and proinflammatory responses in human monocytes. PBMCs were stimulated for 6 hours with PGN (10 µg/mL), heat-killed (hk) B anthracis (107 CFU/mL), LPS (1 µg/mL), or Pam3CSK4 (1 µg/mL) in the presence of BFA before intracellular quantification of TF and TNF-α by flow cytometry. (A) Representative distribution of procoagulant (TF+) and proinflammatory (TNF-α+) responses in PAMP-stimulated monocytes. (B) Average distribution of procoagulant and proinflammatory responses in PAMP-stimulated monocytes in the cohort studied (n = 11). Column segments represent mean and standard deviation for each population depicted in the legend. FITC, fluorescein isothiocyanate.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal