Deficiency in Nox2 does not influence susceptibility to carotid artery thrombosis in male or female mice. The time to stable occlusion of the carotid artery following photochemical injury was measured in male and female WT (+/y or +/+) or Nox2-deficient (−/y or −/−) mice. (A) Time to stable occlusion. (B) Percentage of mice with a patent carotid artery (free of stable occlusion) as a function of time after injury. Data are presented as mean ± standard error (n = 7-10 mice in each group). Data were analyzed using 2-way ANOVA with the Tukey test for multiple comparisons.