A 3-gene PI stratifies survival in adult AML patients (discovery series) with clinically established molecular lesions. (A-C) Kaplan-Meier estimates of EFS and OS. Kaplan-Meier estimates of OS in AML patients who received chemotherapy alone (D) or chemotherapy followed by allogeneic HSCT (E). Survival curves were compared using a log-rank (Mantel-Cox) test.