Figure 1.
SAXS data for ADAMTS13 and C-terminal truncations. (A) Schematic structure of ADAMTS13 and a nested series of C-terminal truncations. (B) Sodium dodecyl sulfate–polyacrylamide gel electrophoresis of selected purified recombinant ADAMTS13 variants. Lane 1 is Precision Plus Protein All Blue Standards (Bio-Rad). (C) Scattering profiles (black) and P(r) plots (inset) for the indicated pure recombinant proteins. P(r) plots for MDTCSq (red) and ADAMTS13 (FLq: blue) are included in each inset panel for comparison with other truncation constructs (green).