Figure 3.
SAXS data, ab initio envelopes, and molecular models of ADAMTS13 internal deletions. (A) Scattering profiles and P(r) plots (inset) for the indicated pure recombinant ADAMTS13 variants. P(r) plots for MDTCSq (red) and ADAMTS13 (FLq: blue) are included in each inset panel for comparison with other deletion constructs (green). (B) Molecular models were fitted into ab initio envelopes (gray surface) calculated from SAXS profiles for the indicated ADAMTS13 constructs.