Critical information to personalize management of patients with MF. (Top) Decision flowchart for each patient with MF suitable for SCT. (Bottom) All prognostic models in use with variables and score in parentheses for assessing risk category to each patient. Dynamic International Prognostic Scoring System (DIPSS) categories: low (0); intermediate-1 (1-2), intermediate-2 (3-4), high risk (5-6); Mutation-Enhanced International Prognostic Score System (MIPSS-70) categories: low (0-1); intermediate (2-4), high risk (≥5); Myelofibrosis Secondary Prognostic model (MYSEC-PM) categories: low (<11); intermediate-1 (11-13), intermediate-2 (14-15), high risk (≥16), http://www.mysec-pm.eu; MTSS categories: low (0-2); intermediate (3-4), high (5), very-high risk (6-9). BM, bone marrow; BMF, bone marrow fibrosis; Cont, continuous; C.S., constitutional symptoms; Hb, hemoglobin value; HMR, high-molecular risk; K., Karnofsky; MMU, mismatched unrelated; mut., mutation; PLT, platelet count; P.S., performance status; WBC, white blood cell count.