Lymphocyte subset and EBV tetramer staining of PBMCs from patients with HV and normal controls. Tetramer staining was performed for EBV LMP2, lytic protein BRLF1, and influenza M1 (flu) with costaining for CD8 (A), CD127 (B), CD27 (C), PD1 (D), CCR7 (E), or CD57 (F). P values are shown for results that are significantly different between patients and controls. NC, normal control; pt, patient.