Donor and recipient CMV status is associated with viral epitope recognition at d100 but not d365 after HCT. (A-C) Dot and whisker plot representing the estimate and 95% CI of total epitopes recognized at d100 (D⁻/R⁻ n = 3; D⁺/R⁻ n = 8; D⁻/R⁺ n = 5; D⁺/R⁺ n = 21) (A) and total epitopes excepting CMV epitopes (C), derived from a generalized linear model accounting for both donor and recipient CMV status. D⁻/R⁺ recognized most epitopes, followed by both D⁺ groups, which shows that CMV confers greater influence than simply the addition of its epitopes to the total epitope count; there is an interaction between donor-recipient dynamics. (B,D) Similar plot at d365, although CMV status of donor or recipient no longer influences total viral epitopes recognized, whether or not CMV epitopes were included.