Fig. 7.
Inhibition of the antiproliferative effect of IFNα on primary thymocytes by recombinant muIfnar-2a.
DNA replication was measured by incorporation of3H-thymidine, and the data presented as the mean ± SEM, (n = 7) percentage inhibition of proliferation. (A) Thymocytes stimulated to proliferate with PHA (40 μg/mL) were incubated with 100 IU/mL (▾) and 10 IU/mL (▴) recombinant muIFNα4, and the indicated concentrations of muIfnar-2a. (B) Percentage stimulation of proliferation of PHA-stimulated thymocytes in the absence of exogenous IFN, by the indicated concentrations of recombinant muIfnar-2a.