Effect of host irradiation on B6.SJL engraftment into BALB/c hosts.

BALB/c recipient mice were either unirradiated or subjected to 100 to 600 cGy WBI and then infused with 40 million B6.SJL marrow cells. The percentage (%) donor (CD45.1⁺) cells in peripheral blood ± 1 SEM are presented out to 21 weeks after transplantation. There were 4 mice per group at 400 cGy and 500 cGy and 5 mice per group at all other levels. After 9 weeks the 100-cGy groups dropped to 4 mice. Values for the 600-cGy group were significantly different from the 0-, 200-, and 300-cGy groups at all time points out to 21 weeks (P < .05).