Engraftment of B6.SJL marrow in C57BL/6 hosts.

Forty million male B6.SJL marrow cells were infused into nonirradiated (0 cGy) or irradiated (100 cGy) C57BL/6 male hosts and percent engraftment in peripheral blood determined out to 21 weeks after transplantation. Data are presented as percentage (%) engraftment ± 1 SEM. There were 5 mice per group and engraftment was evaluated by CD45.1 labeling FACS analysis on individual mice. Values in the 100-cGy group were significantly different from the 0-cGy group at all time points (P < .05). At 21 weeks, engraftment was also determined in marrow, spleen, and thymus, along with peripheral blood. Percent engraftment levels in blood, spleen, thymus, and marrow were 23.2 ±  9.3, 25.3 ± 8.2, 28.4 ± 13.6 and 14.9 ± 5.3, respectively.