Splenic remnant growth over time in patients with HS after subtotal splenectomy.

Mean volume of the spleen is expressed as percentage (%) of normal volume according to body weight. Mean initial splenic volume before surgery was noted to be 492% for 7 individuals (range: 284% to 820%). The hatched area represents the volume of the spleen excised. After 1 year, the regrowth of the remnant led to a normal splenic volume (mean 124% for 10 children). Mean splenic volume value after 2 to 3 (3 children), 4 to 5 (7 children), 6 to 8 (5 children), and 9 to 11 (3 children) years were respectively 207%, 178%, 313%, and 244%. The large mean splenic volume noted at 6 to 8 years after surgery is skewed because of the inclusion of data from 2 children who exhibited unusually large splenic regrowth (422% and 500% of normal).