Effect of rhIL-11 injections in vWf-deficient mice.

Placebo or 250 μg/kg rhIL-11 was administered daily to vWf^−/− mice for 7 days. (A) Platelet counts and (B) FVIII levels were measured before (■) and after (▪) the rhIL-11 treatment for each animal (n = 19-20). *P < .0001 compared with placebo-injected mice.