Figure 2.
Figure 2. Reduction of CLP cells in the BM of cGVHD animals. B10.BR mice were transplanted with BM only or BM and T cells from B6 donor mice, and BM cells from tibiae and femurs were harvested on day 30. (A) Representative flow cytometry plots demonstrating frequency of CLP cells in the Lin−c-KitintSca-1int population in the BM of transplanted animals. (B) Frequency (left) and total number (right) of donor-derived CLP cells isolated from BM of transplanted mice. Combined data from 3 independent experiments are shown. *P < .05 (Mann-Whitney U test); n = 10 in each group. Bars represent standard error of the mean.

Reduction of CLP cells in the BM of cGVHD animals. B10.BR mice were transplanted with BM only or BM and T cells from B6 donor mice, and BM cells from tibiae and femurs were harvested on day 30. (A) Representative flow cytometry plots demonstrating frequency of CLP cells in the Lin−c-KitintSca-1int population in the BM of transplanted animals. (B) Frequency (left) and total number (right) of donor-derived CLP cells isolated from BM of transplanted mice. Combined data from 3 independent experiments are shown. *P < .05 (Mann-Whitney U test); n = 10 in each group. Bars represent standard error of the mean.

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