Figure 3. Overlapping mutational... | American Society of Hematology

Figure 3.

$Figure 3. Overlapping mutational characteristics identified in the 3 cell fractions by targeted sequencing. Mutations present in blast cells (Bla), granulocytes (Gra), and T cells (Tc) in each of the 44 patients (UPN is shown in the second column from the left). Overlapping and nonoverlapping mutations are shown as red and yellow rectangles, respectively. When multiple mutations were identified in the same gene, only a representative mutation is shown for each case. The variant allele frequency (VAF) of each mutation is indicated by the horizontal width of the rectangle, with a maximum value set to 50%. Patient diagnosis (Dx) is shown in the far left-hand panel and is color coded according to the disease subset. The DNMT3A mutation in R882 residue is indicated by asterisks.$

Overlapping mutational characteristics identified in the 3 cell fractions by targeted sequencing. Mutations present in blast cells (Bla), granulocytes (Gra), and T cells (Tc) in each of the 44 patients (UPN is shown in the second column from the left). Overlapping and nonoverlapping mutations are shown as red and yellow rectangles, respectively. When multiple mutations were identified in the same gene, only a representative mutation is shown for each case. The variant allele frequency (VAF) of each mutation is indicated by the horizontal width of the rectangle, with a maximum value set to 50%. Patient diagnosis (Dx) is shown in the far left-hand panel and is color coded according to the disease subset. The DNMT3A mutation in R882 residue is indicated by asterisks.

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