Initial presentation and clinical course. (A) The patient as he appeared at presentation, following rapid development of a mask-like purpuric rash involving the face. (B) Polymorphonuclear leukocyte containing rod-like basophilic inclusions on Wright’s stain (arrowhead; left panel), and Gram’s stain (arrowhead; right panel). Original magnification ×1000. (C) Plasma levels of PC, antithrombin (AT), and lactate during the first 10 days of hospitalization. (D) Activated partial thromboplastin time (aPTT), prothrombin time (PT), and fibrinogen during the same period. PC and antithrombin concentrates were administered twice daily starting 6 hours after presentation through day 10 of hospitalization.