Antibody-induced decreases in the level of detectable antigen are antigen-specific. Posttransfusion, HOD × KEL RBC were stained for the level of detectable KEL antigen (A) or HEL antigen (B). (C) Transfused HOD × KEL RBC were stained for the level of detectable Ter119. Means ± SD shown. ****P < .0001, ***P < .001, and ns by 1-way ANOVA with Tukey multiple comparison test. Data shown include 5 mice per group and are representative of 3 independent experiments.