AML relapse with NPM1^mutoccurs earlier than relapse with NPM1^wt. (A) RFS of patients with NPM1^mut relapse and NPM1^wt relapse. (B) OS following relapse of patients with NPM1^mut relapse and NPM1^wt relapse. 95% CI, 95% confidence interval; OS, overall survival; RFS, relapse-free survival.