Preferential expression of HMGA2 within the primitive compartment of human hematopoietic cells. (A-C) HMGA2 expression measured by quantitative PCR in FACS-purified populations, HSCs (CD34⁺CD38⁻CD45RA⁻CD90⁺), MPPs (CD34⁺CD38⁻CD45RA⁻CD90⁻), MLP (CD34⁺CD38⁻CD45RA⁺CD90⁻), and committed progenitors (CP; CD34⁺CD38⁺) obtained from fetal liver (FL) (A), CB (B), and adult BM (C). (D) Relative expression of HMGA2 mRNA in purified HSCs from different developmental sources. (E) HMGA2 protein expression was assessed by western blot in FACS-purified CB populations. *P < .05; **P < .01; ***P < .001; ****P < .0001. ns, not significant.