Relative frequency of T-cell clonotypes. TCRα (A), TCRβ (B), and TCRγ (C) repertoire sequences identified from WES of MF samples. Sample ID relates to patient number, as in Figure 1, with the suffix P (plaque) or T (tumor). TCRα (D) and TCRβ (E) repertoires identified by WTS of MF samples. Each bar represents an individual CDR3 amino acid clonotype, with red and green indicating the first-ranked and tenth-ranked clonotype, respectively, in decreasing order of relative frequency. Gray bars represent the rest of the identified clonotypes in the samples. NormalLym, pooled CD4⁺ normal lymphocytes from 4 healthy donors.