Immunologic effects on lymphocytes. (A-B) Median absolute numbers of peripheral blood lymphocyte subsets, including CD4⁺ T_con cells, CD8⁺ T cells, B cells, NK cells, NKT cells, and T_reg cells. (C) CD4⁺ T_reg:T_con ratio. Lymphocyte subsets were identified by flow cytometry using specific antibodies described in “Methods.”