Multiorgan leukostasis (case 1). Hematoxylin and eosin–stained sections (original magnification ×20) taken from autopsy showed severe diffuse leukostasis in the brain (A), heart (B), lungs (C), and spinal cord (D). Additionally, the spleen, liver, colon, and uterus displayed similar findings with evidence of ischemia and end-organ damage (not shown).