Proinflammatory cytokines/chemokines are reduced in Fibγ^390-396ASS mice compared with the Fib^WTSS mice. One year post-BMT, blood samples were collected from the experimental mice. Platelet-poor plasma samples were used for cytokine profiling by Luminex assay. (A) IL-6. (B) TNF-α. (C) KC. Similar number of fully chimeric male and female mice were used in the experimental groups. Each symbol in the graph represents an individual mouse. Fib^WT AA/B6 (n = 11-15), Fibγ^390-396A AA/B6 (n = 8-12), Fib^WT SS (n = 17-22), and Fibγ^390-396A SS (n = 17-22). The bars in the graph indicate the mean ± SEM. Statistical significance was determined using 1-way ANOVA followed by the Tukey's multiple comparison test; statistical significance is indicated as **P ≤ .01, *P ≤ .05.