Comparison of LV dimensions, systolic function, and mass. (A-B) LVID;d and LVID;s, respectively. (C) LV FS. (D) Echocardiographically derived LV mass is reduced in Fibγ^390-396A SS compared with the Fib^WT SS mice. Echocardiograms were performed on mixed-sex chimeric mice 12 months after BMT. Data are presented as mean ± SEM. Statistical significance was determined using 1-way ANOVA followed by the Tukey's multiple comparison test; statistical significance is indicated as *P ≤ .05, **P ≤ .01, ***P ≤ .001, ****P ≤ .0001.