Urine albumin, urine volume, and blood creatinine are reduced in Fibγ^390-396ASS mice compared with the Fib^WTSS mice. One year after BMT, urine samples were collected for 24 hours from the experimental mice and albumin concentration was measured by the mouse albumin ELISA kit. (A) Urine albumin (normalized by urine creatinine) is reduced in Fibγ^390-396A SS mice compared with the Fib^WT SS mice. (B) Urine volume is decreased in Fibγ^390-396A SS mice compared with the Fib^WT SS mice. One year after BMT, blood samples were collected from the experimental mice. Platelet-poor plasma samples were used for urea nitrogen and creatinine measurement. (C) Blood creatinine is decreased in Fibγ^390-396A SS mice compared with the Fib^WT SS mice. (D) Blood urea nitrogen shows a trend for reduction in Fibγ^390-396A SS mice compared with the Fib^WT SS mice. (E) Urine osmolality is not improved in Fibγ^390-396A SS mice compared with the Fib^WT SS mice. Similar number of fully chimeric male and female mice were used in the experimental groups. Each symbol represents an individual mouse. The bars in the graph indicate the mean ± SEM. Statistical significance was determined using 1-way ANOVA followed by the Tukey's multiple comparison test; statistical significance is indicated as ***P ≤ .001, **P ≤ .01, *P ≤ .05. (D) For blood urea nitrogen, the Dunn test were used.